Fructose and Uric Acid: If You Have Gout, You Need to Know The Connection
Please note the following article on the relation of fructose and gout :
Drinking just one soda or 6-ounce glass of orange juice a day has been linked to a significant increase in gout – 74 percent and 41 percent, respectively – compared to drinking these only rarely.4 We believe the primary culprit is fructose, which typically generates uric acid within minutes of ingestion. You probably already know that fructose is a sugar, but you may not realize is that it's distinctly different from other sugars as it's metabolized through very specific pathways that differ from those of glucose, for example, and through its distinct metabolic action, uric acid is generated.
For those of you who maintain that "a sugar is a sugar is a sugar,"fructose" - and fructose ALONE -- drives up uric acid. And elevated uric acid levels are not only a factor in gout, they're a factor in many other health conditions, including hypertension, insulin resistance/diabetes, obesity and kidney disease. Not coincidentally, may of these conditions, like diabetes and hypertension, also increase your risk of gout.
The connection between fructose consumption and increased uric acid is so reliable that a uric acid level taken from your blood can actually be used as a marker for fructose toxicity. I now recommend that a uric acid level be a routine part of your blood screening. According to the latest research, the safest range for uric acid is between 3 and 5.5 milligrams per deciliter, and there appears to be a steady relationship between uric acid levels and blood pressure and cardiovascular risk, even down to the range of 3 to 4 mg/dl. As you probably know, two-thirds of the U.S. population is overweight, and most of these people likely have uric acid levels in excess of 5.5. Some may even be closer to 10 or higher (this may explain why being overweight also increases your risk of gout). Dr. Richard Johnson, professor of medicine at the University of Colorado, suggests that the ideal uric acid level is probably around:
- 4 mg/dl for men
- 3.5 mg/dl for women
You can find out more about how uric acid in your blood can cause not only gout but also wreak havoc on your blood pressure, insulin production and even kidney function.